Iinitial rate of DDT-induced aggregation of BSA at 45°C as a function of cross-linked α-crystallin concentration.

<p>The solid line was calculated from Eq. (12) at <i>S</i><sub>0</sub> = 4.7 subunits of α-crystallin per one BSA molecule. The dotted line corresponds to the dependence of (<i>K</i><sub>agg</sub>/<i>K</i><sub>agg,0</sub>)<sup>1/<i>n</i></sup> on concentration of intact α-crystallin (<i>n</i> = 1.6).</p>