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IgM Monoclonal antibody (Moab A7S8).
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posted on 2013-07-16, 03:11 authored by Marcella van Leeuwen, Michael J. Kemna, Menno P. J. de Winther, Louis Boon, Adriaan M. Duijvestijn, Darius Henatsch, Nico A. Bos, Marion J. J. Gijbels, Jan Willem Cohen TervaertA. Reactivity to native, HOCL-oxLDL and MDA-oxLDL. Measured by ELISA, OD 405 at different concentrations (100, 50, 25, 10 and 1 µg/ml IgM concentration). B. Sequence IgM hybridoma. The sequence of Moab A7S8 was compared with germline VH genes by using the international ImMunoGeneTics information system/−QUEry and Standardization (IMGT/V-Quest). Moab A7S8 is composed of IgHV1–78*01, IGHJ3*01 and IGHD1-1*02 alleles, with 100% identity and no gaps. Except for the N-addition, the alleles are in frame germline sequences.
