Figure_4.tif (1.29 MB)
Hydration patterns on the surface of VEGF and the antibody.
figure
posted on 2012-03-22, 01:14 authored by Chung-Ming Yu, Hung-Pin Peng, Ing-Chien Chen, Yu-Ching Lee, Jun-Bo Chen, Keng-Chang Tsai, Ching-Tai Chen, Jeng-Yih Chang, Ei-Wen Yang, Po-Chiang Hsu, Jhih-Wei Jian, Hung-Ju Hsu, Hung-Ju Chang, Wen-Lian Hsu, Kai-Fa Huang, Alex Che Ma, An-Suei Yang(a) Hydration patterns of VEGF are shown as the water oxygen atom PDM contours in cyan on the protein surface and as the color-coded atom surfaces. The water PDMs are shown as 0.0019 contours in this panel. The atom surfaces are color-coded according to the hydration pattern near the atom (Equation (3) in Text S1). (b) The hydration pattern for the G6-Fab (2FJG) is shown.
