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Histological glomerular changes.

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posted on 2013-02-21, 00:05 authored by Oliver Jung, Felix Jansen, Anja Mieth, Eduardo Barbosa-Sicard, Rainer U. Pliquett, Andrea Babelova, Christophe Morisseau, Sung H. Hwang, Cindy Tsai, Bruce D. Hammock, Liliana Schaefer, Gerd Geisslinger, Kerstin Amann, Ralf P. Brandes

Representative kidney sections (magnification ×400) stained by periodide acid - Schiff (PAS) scoring glomerulosclerosis index (GSI) and mesangiolysis score (MSI) after 8 weeks of treatment. Effects of placebo, sEH-inhibition by cAUCB, ACE-inhibition by ramipril (Ramip.) and CYP-inhibition by fenbendazole (Fenbe.) are shown on sham operated (−) and 5-6-Nx (+) animals. * p<0,05 vs. sham, # p<0,05 vs. placebo (n = 5–8/group).

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