Figure_2.tif (287.24 kB)
HBV cccDNA CpG island III methylation is associated with serum HBsAg level.
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posted on 2014-10-22, 03:06 authored by Yongmei Zhang, Richeng Mao, Ran Yan, Dawei Cai, Yijun Zhang, Haoxiang Zhu, Yaoyue Kang, Hongyan Liu, Jinyu Wang, Yanli Qin, Yuxian Huang, Haitao Guo, Jiming Zhang(A) Correlation between serum HBsAg titers and cccDNA CpG island III methylation in patients with chronic HBV infection (r2 = 0.32, P<0.05). (B) The density of CpG island III methylation were significantly higher in patients with low serum HBsAg titer (Log10HBsAg<4) compared to those with high HBsAg level (Log10HBsAg≥4). Dots and squares represent single patient measurement. The median value is indicated with a long line.
