Geographic distribution of <i>dhfr</i> and <i>dhps</i> genotypes, 1990s.

<p>This figure shows the sites examined during the 1990s, noted with red stars, for <i>dhfr</i>. All sites were fixed for the 437G/540E/581G dhps allele, with the exception of one isolate in Itaituba carrying 437G/581G, and therefore these pie charts were omitted The color coding for <i>dhfr</i> appears in the bottom of the map. The data provided for Peixoto de Azevedo, noted by the blue star came from the work of others <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058984#pone.0058984-Vasconcelos1" target="_blank">[45]</a>.</p>