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Gene expression profiles at 15 months post-implantation.

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posted on 2014-06-18, 03:55 authored by Laura Iop, Antonella Bonetti, Filippo Naso, Stefania Rizzo, Stefano Cagnin, Roberto Bianco, Carlo Dal Lin, Paolo Martini, Helen Poser, Paolo Franci, Gerolamo Lanfranchi, Roberto Busetto, Michel Spina, Cristina Basso, Maurizio Marchini, Alessandro Gandaglia, Fulvia Ortolani, Gino Gerosa

Histograms representing enriched Gene Ontology terms for clusters 1, 3, 4 (green and red bars) and 2 (blue bars). P-value ≤0,05 (A). Gene interaction network derived from STRING database analysis of up- and down-regulated genes on A.L. tissues (clusters 1, 3, 4). Pink nodes with grey border connect elements between up- or down-regulated nodes in analyzed clusters. Central color node: gene expression in A.L. tissues; border: B.L. tissues. Yellow edges link connected nodes, while blue edges those altered in analyzed clusters. Purple gene names represent relevant nodes according to Centiscape algorithm. *Genes discussed in the text (B).

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    anatomybiological tissueConnective tissueCardiovascular anatomybiotechnologyBioengineeringBiomedical EngineeringTissue engineeringbiomaterialsMedical devices and equipmentcell biologyCellular structures and organellesExtracellular matrixMolecular cell biologycardiologyCardiovascular diseasesValvular diseasesprofiles15months

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