Expression of TLR4 and its endogenous ligands was upregulated in the early diabetic kidney in WT mice.

<p>mRNA expression of TLR4 and its ligands in kidney was upregulated at 10 weeks after diabetes induction (A & B). The data are presented as means ± SD; * <i>p</i><0.05; ** <i>p</i><0.01; *** <i>p</i><0.001. n = 7 per group. (C) Representative sections of kidney were stained with a rabbit anti-mouse-TLR4 polyclonal antibody in the top panels and a goat anti-mouse-TLR4 polyclonal antibody in the bottom panels.</p>