Figure_2.tif (672.3 kB)
Expression of Rora in the lung tissue of wildtype (WT) and Npsr1 deficient (Npsr1−/−) mice.
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posted on 2013-04-03, 08:25 authored by Nathalie Acevedo, Annika Sääf, Cilla Söderhäll, Erik Melén, Jami Mandelin, Christina Orsmark Pietras, Sini Ezer, Piia Karisola, Johanna Vendelin, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Harri Alenius, Erika von Mutius, Gert Doekes, Charlotte Braun-Fahrländer, Josef Riedler, Marianne van Hage, Mauro D’Amato, Annika Scheynius, Göran Pershagen, Juha Kere, Ville Pulkkinen(A) Lung tissue was collected from WT and Npsr1−/− mice at 4 h intervals, and diurnal mRNA expression of Rora was measured with real-time PCR (n = 3–4/group/timepoint). The black bar represents the dark period. (B) Expression of Rora in the lung tissue of wildtype and Npsr1−/− mice during the light period (8–12 am) (n = 6). Data are expressed as relative units indicating a fold change in Rora mRNA expression that is normalized to an endogenous reference gene (18S ribosomal RNA) and is relative to the non-template control calibrator (mean ± SEM). Similar data were obtained in two separate experiments. *p<0.05.
