Figure_9.tif (993.95 kB)
Experimental infection of Swiss new born and IFNAR(−/−) adult mice with wt and ΔNS4 viruses.
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posted on 2013-02-20, 10:32 authored by Maxime Ratinier, Marco Caporale, Matthew Golder, Giulia Franzoni, Kathryn Allan, Sandro Filipe Nunes, Alessia Armezzani, Amr Bayoumy, Frazer Rixon, Andrew Shaw, Massimo PalmariniSurvival plots of either 3-days old mice inoculated intracerebrally or adult sv129 IFNAR(−/−) inoculated intraperitoneally with the following viruses: BTV-8 (dark red, square), BTV8-ΔNS4 (red, triangle), BTV-1 (blue, square) and BTV1-ΔNS4 (light blue, triangle) viruses. Mock-infected mice are shown in gray, circle. Mice were killed at two weeks post-inoculation, or earlier, if showing advanced clinical signs of systemic disease.
