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Enhanced CD95 mediated apoptosis of T and B cells upon IL-7 treatment.
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posted on 2013-02-20, 10:50 authored by Stefano Sammicheli, Linh Dang Vu Phuong, Nicolas Ruffin, Thang Pham Hong, Rebecka Lantto, Nancy Vivar, Francesca Chiodi, Bence RethiKinetics of CD95 expression (left panels) and CD95 mediated apoptosis sensitivity (right panels) of CD3+ T cells (A) and CD19+ B cells (B) are shown, measured in PBMC cultures treated with 25 ng/ml IL-7, with supernatants of IL-7 treated or non treated T cell cultures or left untreated. Apoptosis was triggered using recombinant CD95L added for 24 hours to cultures. Data are representative of 3 independent experiments.
