Fig_3.tif (1.53 MB)
Enforced expression of human ANGPTL2 increased adipose tissue macrophages and promoted M1 macrophage polarization in adipose tissue from db/db mice.
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posted on 2015-07-01, 04:45 authored by Yusuke Sasaki, Masayuki Ohta, Dhruv Desai, Jose-Luiz Figueiredo, Mary C. Whelan, Tomohiro Sugano, Masaki Yamabi, Wataru Yano, Tyler Faits, Katsumi Yabusaki, Hengmin Zhang, Andrew K. Mlynarchik, Keisuke Inoue, Ken Mizuno, Masanori AikawaA, Stromal vascular fraction (SVF) was isolated from the epididymal fat pad then stained with F4/80, CD11b, and CD11c antibodies and analyzed by FACS. B, Adipose tissue macrophage number was determined as F4/80+ and CD11b+ fraction and determined by FACS (n = 7–8). Data are mean ± SEM, **: P<0.01, *: P<0.05 compared with LacZ group.
