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Effect tBH and DAB on glucose utilization and glycogen mobilization in WT and GCLM-KO astrocytes.

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posted on 2013-02-20, 16:16 authored by Suzie Lavoie, Igor Allaman, Jean-Marie Petit, Kim Q. Do, Pierre J. Magistretti

A- glucose utilization was increase in WT astrocytes following a 40-min treatment with 10 µM and 50 µM tBH in the presence of DAB. n = 6. B- glucose utilization was increase in KO astrocytes following a 40-min treatment with 50 µM tBH in the presence of DAB. n = 11–12. C- glycogen levels were not changed following DAB treatment, but were highly significantly decreased following 40-min tBH treatment in WT astrocytes. n = 9. D- glycogen levels were not significantly affected by either DAB or tBH treatment in GCLM-KO astrocytes. n = 6–9. § p<0.05 vs no tBH; §§§ p<0.001 vs no tBH; ** p<0.01 vs other genotype; *** p<0.001 vs other genotype; n.s., non significant.

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