Figure_7.tif (294.18 kB)
Effect of the c.-428A>T restoring mutation.
figure
posted on 2013-03-22, 07:34 authored by Gianluca Occhi, Daniela Regazzo, Giampaolo Trivellin, Francesca Boaretto, Denis Ciato, Sara Bobisse, Sergio Ferasin, Filomena Cetani, Elena Pardi, Márta Korbonits, Natalia S. Pellegata, Viktoryia Sidarovich, Alessandro Quattrone, Giuseppe Opocher, Franco Mantero, Carla ScaroniIn both GH3 and HeLa cell lines c.-428A>T almost restores the modulation properties of the CDKN1B wild type uORF (A). Panel B shows the primary sequence differences in the wild type uORF compared with the -456_-453delCCTT+c.-428A>T.
