Effect of antimalarial treatment on the number of glomerular cells.

<p>Animals were euthanized on day 5 or day 21 p.i., perfused, and the kidneys were collected for histologic analysis. The number of glomerular cells in the renal cortex was visualized using periodic acid−Schiff. Representative photomicrography of noninfected mice (control<sub>5d</sub>) (<b>A</b>), 5 days p.i. (infected<sub>5d</sub>) (<b>B</b>), noninfected mice that received treatment with antimalarial drugs (control+treated<sub>21d</sub>) (<b>C</b>), and infected mice that received treatment with antimalarial drugs (infected+treated<sub>21d</sub>) (<b>D</b>) (<i>n</i> = 6 per group). Bar = 40 µm. The number of glomerular cells is quantified in (<i>E</i>). The results are expressed as means ± standard error. *Statistically significant compared with control<sub>5d</sub> or control+treated<sub>21d</sub>. #Statistically significant compared with control<sub>5d</sub> or infected<sub>5d</sub> (<i>P</i><0.05).</p>