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Effect of TLR4 siRNA and PDTC treatment on plasma LPS and LBP levels.

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posted on 2015-04-10, 03:01 authored by Ya Ling Tang, Jian Hong Jiang, Shuang Wang, Zhu Liu, Xiao Qing Tang, Juan Peng, Yong-Zong Yang, Hong-Feng Gu

(A) LPS and (B) LBP levels were determined by commercially available kits following the manufacturer’s instructions. The plasma levels of LPS and LBP in the control group, CUMS + siRNA group, and CUMS + PDTC group were significantly lower than those in the CUMS group. The agents (siRNA and PDTC) were given to mice 30 min before the stress exposure. Data are mean ± SEM (n = 15 per group). *P < 0. 05, **P < 0.01.

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