Early postischemic response in FGF1/Tek and control animals.

A. Expression of the kidney injury marker 1, Havcr1, in the postischemic kidneys of FGF1/Tek and control WT FVB mice one day after ischemia. qRT-PCR results normalized to ß-actin expression. Kidneys of five FGF1/Tek and five WT mice were studied. Mean and SEM are presented. B. PAS staining of the paraffin sections of postischemic and contralateral kidneys of control WT FVB and FGF1/Tek mice. One day after ischemia, hematoxylin counterstaining. Bar –40 μ C. Increase of the percentage of tubules with enlarged lumen (lumen occupies more than ¼ of tubule section) in postischemic kidneys comparatively to contralateral organs. Kidneys of four FGF1/Tek and four WT mice were studied. Mean and SEM of fold increase are presented. D. Glomeruli diameters in postischemic and contralateral kidneys. Kidneys of four FGF1/Tek and four WT mice were studied. Mean and SEM are presented.