ESX-5-dependent surface proteins of <i>M</i>. <i>marinum</i>.

<p>* Average normalized spectral counts from two biological replicates</p><p>Cell surface enriched and cell envelope proteins of <i>M</i>. <i>marinum</i>::<i>mspA and Δesx-5</i>::<i>mspA</i> strains were analyzed by LC-MS/MS. Proteins were classified as secreted proteins when the relative normalized abundance was four times higher in the cell-surface enriched fractions as compared to the cell envelope. Shown here are only proteins with at least a five-fold decrease in spectral counts in the Δ<i>esx-5</i>::<i>mspA</i> strain. Rows in bold indicate proteins with restored secretion in the presence of <i>esx-5</i><sub><i>tub</i></sub>.</p><p>ESX-5-dependent surface proteins of <i>M</i>. <i>marinum</i>.</p>