ESX-5-dependent surface proteins of M. marinum.

* Average normalized spectral counts from two biological replicates

Cell surface enriched and cell envelope proteins of M. marinum::mspA and Δesx-5::mspA strains were analyzed by LC-MS/MS. Proteins were classified as secreted proteins when the relative normalized abundance was four times higher in the cell-surface enriched fractions as compared to the cell envelope. Shown here are only proteins with at least a five-fold decrease in spectral counts in the Δesx-5::mspA strain. Rows in bold indicate proteins with restored secretion in the presence of esx-5tub.

ESX-5-dependent surface proteins of M. marinum.