Figure_5.tif (496.26 kB)
EGR-2 deficient mice mount a normal T cell response against LCMV.
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posted on 2013-02-20, 23:17 authored by Hilda E. Ramón, Pedro J. Cejas, David LaRosa, Adeeb Rahman, John E. Harris, Jidong Zhang, Christopher Hunter, Yongwon Choi, Laurence A. TurkaWT or EGR-2 CKO mice were infected with 2×105 PFU of LCMV Armstrong. (A) The number of CD8 T cells specific for gp33 or np396 was measured by staining with MHC-class I tetramers, on days 5, 8, and 15. (B) The percentage of CD8 cells that were IFN-γ producers was analyzed by intracellular cytokine staining after restimulation with LCMV pooled peptide. For all graphs, three mice were analyzed for each genotype on each time point.
