Dynamic Bayesian Gene Group Activation (DBGGA) Pathway analysis.

(A) Summary table of cellular pathways significantly activated or repressed (Bayesian score ≥|2.24|) over the time course of the experiment as determined by the DBGGA tool. (B-C) Read out and heat map of significantly perturbed pathways during days post inoculation (p.i.). Red color indicates activation, green color indicated repression. Intensity of color represents amplitude of perturbation. Analyses are oriented to the Early Phase (days 2–6 p.i.) (B) or the Late Phase (days 7, 10, 14, 21 p.i.) (C) to identify significant perturbations at different periods during the vaccine response.