Figure_4.tif (421.94 kB)
Downregulation of IGF-1R revealed with Western blot analysis of IGF-1Rβ in (A) MCF7 and HT-29 cells treated with hR1, MAB391, 24–60, and hLL2;
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posted on 2012-08-31, 01:08 authored by Chien-Hsing Chang, Yang Wang, Preeti Trisal, Rongxiu Li, Diane L. Rossi, Anju Nair, Pankaj Gupta, Michele Losman, Thomas M. Cardillo, Edmund A. Rossi, David M. Goldenberg(B) MCF7 and HT-29 cells treated with hR1 or Hex-hR1; (C) MCF7, DU 145, and LNCaP cells treated with hR1, Hex-hR1, or hRS7 (irrelevant IgG); (D) MCF-7L cells treated with Hex-hR1 or hMN-15 (irrelevant IgG). In all experiments, β-Actin was used as a loading control.
