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Diminished production of insulin autoantibodies (IAA) in SR-A−/− NOD mice.

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posted on 2014-10-24, 17:49 authored by Mami Shimizu, Hisafumi Yasuda, Kenta Hara, Kazuma Takahashi, Masao Nagata, Koichi Yokono

Sera from 8-, 12-, 16-, and 20-week-old SR-A−/− NOD, SR-A+/− NOD and NOD female littermates were collected and analyzed by our standard IAA assay. Levels of IAA were significantly lower than NOD mice in 16- and 20-week-old SR-A−/− NOD littermates (* p<0.05 by Mann–Whitney U test).

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