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Deuterium incorporation for peptic fragments derived from MM1 rPrP^Sc (red) and MM2 rPrP^Sc(blue).

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posted on 2015-04-14, 03:31 authored by Jiri G. Safar, Xiangzhu Xiao, Mohammad E. Kabir, Shugui Chen, Chae Kim, Tracy Haldiman, Yvonne Cohen, Wei Chen, Mark L. Cohen, Witold K. Surewicz

(a) 5 min incubation in D₂O. (b) 240 h incubation in D₂O. Error bars indicate standard deviation (3 independent experiments). *, P<0.05; **, P<0.02.

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histidine side chains Prion diseases prion protein aggregates data murine prion strains

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Deuterium incorporation for peptic fragments derived from MM1 rPrPSc (red) and MM2 rPrPSc(blue).