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Determination of the effective dose of ivy extract in combination with oseltamivir.
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posted on 2015-06-22, 03:42 authored by Eun-Hye Hong, Jae-Hyoung Song, Aeri Shim, Bo-Ra Lee, Bo-Eun Kwon, Hyuk-Hwan Song, Yeon-Jeong Kim, Sun-Young Chang, Hyeon Gun Jeong, Jong Geal Kim, Sang-Uk Seo, HyunPyo Kim, YongSoo Kwon, Hyun-Jeong KoThe survival rate (A) and body weight (B) of PR8-infected mice administered oseltamivir (*P<0.05; **P<0.01; ***P<0.001, two-tailed unpaired t-test). C: Survival rate of PR8-infected mice that received ivy extract or vehicle (PBS). D: Survival rate of PR8-infected mice that received oral coadministration of ivy extract and oseltamivir (*P<0.05, log-rank analysis of Mantel-Cox data) E: Body weight of PR8-infected mice that received oral coadministration of ivy extract and oseltamivir (*P<0.05, one-way ANOVA with Tukey’s post hoc test).
