Design of round-robin cross to map salt and caffeine resistance.

<p>(<b>A</b>) Phenotyping of 65 diverse strains. Growth under the indicated condition (YPD plus 1 M sodium chloride (NaCl) or 15 mM caffeine) was adjusted for growth under the permissive YPD condition (<a href="" target="_blank">S1 Table</a>). We picked strains (filled symbols) that are representative of the genetic and phenotypic diversity and crossed them according to a round-robin design (<b>B</b>). Strains were crossed independent of phenotype and genetic relationship. Strain name colors indicate mating type (Green  =  MATa, Red  =  MATα).</p>