Demographic and clinical characteristics of all patients at baseline, and in the subgroups of CKD patients stages 1-3a (creatinine clearance ≥45 ml/min) and stage 3b-4 (creatinine clearance ≥15 and <45 ml/min).

Abbreviations: BMI, body mass index; CCl, creatinine clearance; MAP, mean arterial pressure; P_osm, plasma osmolarity; U_osm, urine osmolarity; ACEI/AT-II, angiotensin converting enzyme/angiotensin II receptor antagonist; CCB, calcium channel blocker. Values are given as median (Q1-Q3), if not stated otherwise.