D<sub>h</sub>, PSD and zeta potential of the polymeric vesicles, DOX-loaded vesicles, DOX-loaded chitosan-caged vesicles and DOX-loaded GCPVs in aqueous solutions at 25°C.

a<p>Determined by DLS (Malvern Zetasizer Nano-ZS instrument) at a scattering angle of 173<sup>o</sup>, using the cumulant analysis method.</p>