Figure_4.tif (540.66 kB)
DMSO pre-treatment changes action potential threshold in CA1-PC.
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posted on 2014-03-19, 03:17 authored by Francesco Tamagnini, Sarah Scullion, Jonathan T. Brown, Andrew D. RandallA) Averaged action potential waveform ± SEM from 20 control cells (aCSF) and 24 DMSO treated cells. The action potentials were the first spike to fire in response to a 300 pA depolarizing stimulus. B) Cell by cell analysis of action potential parameters for the action potentials used to compile (A). DMSO caused a negative shift in action potential threshold (P<0.03).
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anatomynervous systemcell biologyCellular typesAnimal cellsneuronsMolecular cell biologyComputational biologycomputational neuroscienceSingle neuron functionneurosciencephysiologyelectrophysiologytoxicologyNeurotoxicologySpecimen preparation and treatmentMechanical treatment of specimensSpecimen disruptionelectroporationpre-treatment
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