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Correlation of high mRNA expression and shortened survival of HNSCC patients.
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posted on 2014-10-02, 03:54 authored by Rolf Warta, Dirk Theile, Carolin Mogler, Esther Herpel, Niels Grabe, Bernd Lahrmann, Peter K. Plinkert, Christel Herold-Mende, Johanna Weiss, Gerhard DyckhoffClassification of HNSCC patients according to the expression level of the respective gene in high (n = 20) or low (n = 20) expression group. Survival analysis by Kaplan-Meier curves and log rank test revealed that patients with high gene expression tended to accompany a shorter progression-free and overall survival.
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drug efflux transportersABCG 2Stage IV HeadCancer Genome Atlas databasesurvivalmrpïve stage IV headoscopper transporter ATP 7b mRNA expressiontranscription polymerase chain reactionbcrpAnalyzing mRNA expression levels31ANeck Squamous Cell Carcinoma Drug transportersabcctmadrug transportersDrug Transporter ExpressionHigh ABCB 1 mRNA tumor expressionhnsccslcProtein expressionpfs
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