Fig_3.tif (520.78 kB)

Correlation of circulating anodic antigen (CAA) levels and S. haematobium egg counts or microhematuria grading.

figure

posted on 2015-05-14, 02:58 authored by Stefanie Knopp, Paul L. A. M. Corstjens, Artemis Koukounari, Colin I. Cercamondi, Shaali M. Ame, Said M. Ali, Claudia J. de Dood, Khalfan A. Mohammed, Jürg Utzinger, David Rollinson, Govert J. van Dam

(A) Correlation of CAA levels (pg/ml) in 1.5 ml of urine and the number of S. haematobium eggs detected in 10 ml of urine (Spearman’s rho = 0.24; P <0.001); (B) correlation of CAA levels (pg/ml) and the microhematuria grading (Spearman’s rho = 0.23; P <0.001); and (C) correlation of S. haematobium eggs detected and microhematuria grading (Spearman’s rho = 0.57; p<0.001), in urine samples from children from Pemba, United Republic of Tanzania, collected in 2013. The horizontal continuous red line indicates the cut-off value of >0.4 pg/ml for samples clearly indicated as S. haematobium-positive by the UCAA2000 (A and B). The horizontal dotted red line indicates the cut-off value of <0.2 pg/ml for samples clearly indicated as S. haematobium-negative by the UCAA2000 (A and B). Values right from the vertical continuous red line (A) and above the horizontal continuous red line (C) indicate egg-positive urine filtration tests