Fig_3.tif (2.97 MB)
Confocal microscopy analysis of PKH26-labeled BMSC-EVs localization in colon after injection.
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posted on 2015-10-15, 03:38 authored by Jia Yang, Xing-Xing Liu, Heng Fan, Qing Tang, Zhe-Xing Shou, Dong-Mei Zuo, Zhou Zou, Meng Xu, Qian-Yun Chen, Ying Peng, Shuang-Jiao Deng, Yu-Jin LiuThe localization was measured 12h after intravenous injection. (A-I) Representative micrograph of inflammatory colon with the treatment of PKH26-labeled BMSC-EVs (red) at the dose of 50, 100 and 200μg. In merge images, nuclei were stained with DAPI (blue). Original magnification×200.
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superoxide dismutasedaiapoptosigshAttenuating Colon InflammationtnbsDisease Activity Indexcolitis ratsExtracellular Vesicles DerivedTissue repairbone mesenchymalparacrine mechanismparacrine activityExtracellular VesiclescoxBone Marrow Mesenchymal Stem Cells Protectinterleukinoxidative stresscaspasebmscExperimental ColitismrnaIntravenous injectionmpoCell communicationoxidative perturbationsmdanfinflammation responseTherapeutic effectfactor kappaBp 65protein levelstnfilsod
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