Comparison with other transcriptomes.
A. Cutaneous localization of MAD-5 transcriptome. 49% of MAD-5 genes (black rectangle) were identified as being part of the Epidermis (green rectangle) or Dermis (yellow rectangle) psoriasis transcriptome defined by the use of laser capture micro-dissection (LCM) techniques (using the same cutoffs FDR<0.05 and FCH>2). Genes identified in both Epidermis and Dermis transcriptomes are in the blue rectangle. B. Venn-Diagram showing the intersection between the MAD-3 psoriasis transcriptome and RNA-seq pilot experiment (using the same cutoffs FDR<0.05 and FCH>2). Numbers are colored in red and green to represent up-regulated or down-regulated genes respectively. The gray zone represents genes identified by RNA-seq but that were not physically present in the hgu133plus2 chips.