Figure_2.tif (5.3 MB)
Combined effects of DAT1 and COMT genotypes on early visual contingent negative variation (CNV).
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posted on 2013-02-20, 02:08 authored by Stephan Bender, Thomas Rellum, Christine Freitag, Franz Resch, Marcella Rietschel, Jens Treutlein, Christine Jennen-Steinmetz, Daniel Brandeis, Tobias Banaschewski, Manfred LauchtTop: The effect of the COMT genotype on the time course of the visual early CNV is shown separately for the homozygous 6R–10R DAT1 haplotype and the DAT1 haplotype with at least one non-6R–10R allele. The same conventions as for Figure 1 apply. Bottom: Topography of the visual early CNV (600–900 ms after the cue ‘A’) – combined influences of DAT1 and COMT genotypes. Note that there were nearly no changes in visual early CNV topography but especially in the presence of the homozygous 6R–10R DAT1 haplotype, the Met/Met COMT genotype increased visual occipito-temporal early CNV amplitude.
