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Clusters and Pathways.

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posted on 2010-07-22, 00:23 authored by Christopher M. Bryant, Daniel L. Albertus, Sinae Kim, Guoan Chen, Christian Brambilla, Mickael Guedj, Chinatsu Arima, William D. Travis, Yasushi Yatabe, Takashi Takahashi, Elisabeth Brambilla, David G. Beer

Tumors with lower levels of the cell cycle stimulatory (CC+) were more likely to be in Cluster 1 or 2, other pathways held constant. Tumors with higher levels of the IGF-1 pathway were more likely to be in Cluster 2 and less likely to be in Cluster 1. Samples with increased antigen pathway expression were more likely to be in Cluster 2 and less likely to be in Cluster 3. Tumors with increased complement pathway expression were more likely to be in Cluster 1 and less likely to be in Cluster 3. NA indicates that the variable was excluded during model selection and thus deemed unimportant.

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