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Circulating PD-L1 expression was closely correlated with their corresponding intratumoral PD-L1 expression.

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posted on 2013-02-20, 15:11 authored by Zhen Zeng, Feng Shi, Lin Zhou, Min-Na Zhang, Yan Chen, Xiu-Juan Chang, Yin-Ying Lu, Wen-Lin Bai, Jian-Hui Qu, Chun-Ping Wang, Hong Wang, Min Lou, Fu-Sheng Wang, Ji-Yun Lv, Yong-Ping Yang

(A)Representative immunohistochemical results of PD-L1 for different degrees are shown(red for PD-L1, ×400). (B) Statistical analysis demonstrated that circulating PD-L1 was significantly correlated with intratumoral PD-L1(r = 0.706, P<0.001). (C) The predictive ability of circulating PD-L1/PD-1 compared with that of intratumoral PD-L1 by receiver operating characteristic (ROC) curves for overall survival (OS).

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