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Chronic infection with Trypanosoma cruzi modulates circulating memory B cell subsets.
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posted on 2014-08-11, 03:43 authored by Esteban R. Fernández, Gabriela C. Olivera, Luz P. Quebrada Palacio, Mariela N. González, Yolanda Hernandez-Vasquez, Natalia María Sirena, María L. Morán, Oscar S. Ledesma Patiño, Miriam Postan(A) Representative samples from a control donor and a T. cruzi-infected individual. PBMC were stained with Abs to CD19, CD27, IgD, IgM and IgG, and analyzed by flow cytometry. Numbers correspond to the percentage of cells within the gate. (B) Box and whiskers (min to max) show the percentage of cells expressing the indicated markers for control (n = 8) and infected individuals (n = 18). Groups were compared by the Mann-Whitney nonparametric test or U-test and statistical significance (p values) is indicated.
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cell biologyCellular typesAnimal cellsBlood cellsWhite blood cellsb cellsMemory B cellsImmune cellsAntibody-producing cellsimmunologyClinical immunologyInfectious disease immunologyImmune responseAntibody responseimmunomodulationParasitic diseasesProtozoan infectionsChagas diseaseTropical diseasesneglected tropical diseasesmodulatescirculating
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