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Chronic exposure of human PAC to nicotine decreases carrier-mediated [3H] thiamin uptake.

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posted on 2015-12-03, 14:16 authored by Padmanabhan Srinivasan, Edwin C. Thrower, Gopalakrishnan Loganathan, A. N. Balamurugan, Veedamali S. Subramanian, Fred S. Gorelick, Hamid M. Said

Human PAC were exposed to nicotine (0.5 μM, 48 h) and carrier-mediated uptake of 3H-thiamin was determined as described under “Materials and Methods”. Data represents the mean ± SE of at least three separate uptake determinations.*P < 0.01.

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    PACSLC 19Athiamin uptake processPancreatic acinar cellsnicotineTHTRChronic Nicotine ExposurePancreatic Acinar Cells Thiaminexpressionthiamin uptakeVitro Inhibits Vitamin B 1exposureSLC 19A genes

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