Figure_1.tif (203.93 kB)
Chemical structures of published CHK2 inhibitors.
figure
posted on 2013-06-12, 02:09 authored by M. Cris Silva-Santisteban, Isaac M. Westwood, Kathy Boxall, Nathan Brown, Sam Peacock, Craig McAndrew, Elaine Barrie, Meirion Richards, Amin Mirza, Antony W. Oliver, Rosemary Burke, Swen Hoelder, Keith Jones, G. Wynne Aherne, Julian Blagg, Ian Collins, Michelle D. Garrett, Rob L. M. van Montfort1, The guanylhydrazone PV1019; 2, the isothiazole carboxamidine VRX0466617; 3, the 2-(quinazolin-2-yl-phenol inhibitor CCT241533; 4, the indoloazepine derivative of hymenialdisine; 5, a 2-arylbenzimidazole-5-carboxamide; 6, the staurosporine analog UCN-01; the dual CHK1/CHK2 inhibitors 7, AZD7762; 8, LY2606368; 9, PF-00477736; and 10, a 2-aminopyridine inhibitor CHK2 inhibitor.
