posted on 2014-01-09, 02:57authored byKatrin Ingram-Sieber, Noemi Cowan, Gordana Panic, Mireille Vargas, Nuha R. Mansour, Quentin D. Bickle, Timothy N. C. Wells, Thomas Spangenberg, Jennifer Keiser
In vitro activity on P. falciparum 3D7, NTS, adult S. mansoni, cytotoxicity on MRC5-cells, and pharmacokinetic parameters* of 5 active compounds selected for in vivo studies identified in 2 parallel screens at the Swiss TPH and LSHTM.