Casticin significantly enhanced TRAIL-induced cytotoxicity of gastric cancer cells.

<p>Effects of casticin (A) and TRAIL (B) alone, or a combination treatment of casticin and TRAIL (C) on cytotoxicity of BGC-823, SGC-7901, and MGC-803 cells (mean±SD, <i>n</i> = 3). <sup>*</sup><i>P<0.05</i> vs. treatment with DMSO; <sup>#</sup><i>P<0.05</i> vs. treatment with 1 µmol/l casticin or 25 ng/ml TRAIL or treatment with TRAIL at the same concentration alone. Effects of casticin and TRAIL alone, or a combination treatment of casticin and TRAIL on cytotoxicity of GES-1 cells (D).</p>