Figure_7.tif (783.15 kB)
Casticin induced DR5 and CHOP upregulation and enhanced TRAIL-induced apoptosis of BGC-823 cells in a ROS-dependent manner.
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posted on 2013-03-12, 09:02 authored by Yuan Zhou, Li Tian, Lingzhi Long, Meifang Quan, Fei Liu, Jianguo CaoEffects of casticin on ROS generation (A and B) and the effects of NAC on casticin-induced DR5 and CHOP upregulation (C) using western blot analysis and TRAIL-mediated apoptosis (D) in BGC-823 cells (mean±SD, n = 3). *P<0.05 vs. treatment with DMSO; #P<0.05 vs. treatment with 1 µmol/l casticin plus 50 ng/ml TRAIL in cells pretreated with NAC.
