Figure_6.tif (335.49 kB)
CTLA4Ig directly activates NK-92MI cells to induce marked expression of the NK cell effector molecules NKG2D and NKp44.
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posted on 2013-12-11, 02:50 authored by Yanmeng Peng, Gaoxing Luo, Junyi Zhou, Xiaojuan Wang, Jie Hu, Yanyan Cui, Xian C. Li, Jianglin Tan, Sisi Yang, Rixing Zhan, Junjie Yang, Weifeng He, Jun Wu(A) Expression of CD86 on NK-92MI cells was analyzed by flow cytometry. One representative experiment of four is shown. (B) Flow cytometry was used to assess the expression of the activation receptors NKG2D on NK-92MI cells treated with either CTLA4Ig or isotype IgG or IL-2 for 24 hours. One representative experiment of four is shown. **p < 0.0001 was considered as statistically significant when compared with the control group. (C) Flow cytometry was used to assess the percentage of NKp44 positive NK-92MI cells after treated with either CTLA4Ig or isotype IgG or IL-2 for 24 hours. One representative experiment of four is shown.
