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CRAI with 5-Fu and Octreotide (Oct) increased the ratio of TXB2 to 6-k-PGF1α.

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posted on 2013-02-20, 04:41 authored by Meng Tao Zhou, Bi Cheng Chen, Hong Wei Sun, Yue Peng Jin, Fa Jing Yang, Xing Zhang, Roland Andersson, Qi Yu Zhang

No significant difference of TXB2 was found among the 4 experimental groups. However, 6-k-PGF1α significantly increased in all 3 treatment groups. So the ratio of TXB2 to 6-k-PGF1α was significantly lower in the treatment groups as compared to the SAP group. The sham group had normal TXB2, 6-k-PGF1α, and ratio of TXB2 to 6-k-PGF1α. *: vs. SAP group, P<0.05; ☆: vs. SAP group, P<0.01; $: 5-FU group vs. Oct group, P<0.05; $$: 5-FU group vs. Oct group, P<0.01; #: 5-FU group or Oct group vs. 5-FU + Oct group, P<0.05; ##: 5-FU group or Oct group vs. 5-FU + Oct group, P<0.01.

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