Figure_5.tif (1.37 MB)
COX-2 function is linked with Myc in regulating glycolysis and glutaminolysis in the COX-2-overexpressing, celecoxib-resistant SUM149-CER cell line.
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posted on 2012-05-03, 01:04 authored by Balraj Singh, Karen Tai, Simran Madan, Milan R. Raythatha, Amanda M. Cady, Megan Braunlin, LaTashia R. Irving, Ankur Bajaj, Anthony LucciWe transfected SUM149-CER cells with a COX-2-specific siRNA or with a control siRNA and analyzed the levels of Myc and some proteins involved in Myc-mediated glycolysis (hexokinase II and lactate dehydrogenase A) and glutaminolysis (glutaminase) by western blotting.
