Figure_1.tif (9.7 MB)
CCCP decreased TMRE signals in ex vivo perfused hearts.
figure
posted on 2015-01-16, 02:41 authored by Akira Kawamoto, Takao Kato, Tetsuo Shioi, Junji Okuda, Tsuneaki Kawashima, Yodo Tamaki, Shinichiro Niizuma, Yohei Tanada, Genzou Takemura, Michiko Narazaki, Tetsuya Matsuda, Takeshi Kimura(A) Schematic of the experiment. Hearts were perfused with TMRE, and the signals were observed using two-photon laser microscopy. The images were obtained serially from hearts perfused with buffer containing vehicle or CCCP (0.1 or 1 μM). (B) Representative images of TMRE signals. Scale bar: 50μm. (C) CCCP decreased the TMRE signals of perfused hearts in a dose-dependent manner 20 min after CCCP perfusion (n = 3–4 per group). *P < 0.05 versus vehicle.
