Figure_1.tif (373.75 kB)
Body weight (A) and heart weight gain (B) as well as heart to body weight ratio (C) of AT2 receptor-deficient (KO) and wild-type (WT) mice during development.
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posted on 2012-10-29, 00:36 authored by Daniel Biermann, Andreas Heilmann, Michael Didié, Saskia Schlossarek, Azadeh Wahab, Michael Grimm, Maria Römer, Hermann Reichenspurner, Karim R. Sultan, Anna Steenpass, Süleyman Ergün, Sonia Donzelli, Lucie Carrier, Heimo Ehmke, Wolfram H. Zimmermann, Lutz Hein, Rainer H. Böger, Ralf A. BenndorfAccelerated cardiac and body weight gain in postnatal KO as compared to WT mice resulting in a significantly reduced heart to body weight ratio of neonatal and adolescent KO mice. In contrast, the heart to body weight ratio of adult eight week-old KO mice is significantly increased. * P<0.001 vs. WT (n = 43–233/36–210). Data are shown as mean ± SEM.
