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Bioinformatics analysis of transcription factors enriched in the BCAA metabolic pathway genes up-regulated in PGC-1α Tg mice.

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posted on 2014-03-17, 03:57 authored by Yukino Hatazawa, Miki Tadaishi, Yuta Nagaike, Akihito Morita, Yoshihiro Ogawa, Osamu Ezaki, Takako Takai-Igarashi, Yasuyuki Kitaura, Yoshiharu Shimomura, Yasutomi Kamei, Shinji Miura

List of transcription factors, which are statistically identified as ones that can be recruited to the BCAA metabolic genes, up-regulated in PGC-1α Tg mice. Target genes were previously found in ChIP assay for interacting with indicated transcription factors in the literature [27]. Abbreviations of the transcription factors are as follows, KLF4, Krueppel-like factor 4; PPARG, Constitutive coactivator of peroxisome proliferator-activated receptor gamma (Constitutive coactivator of PPAR-gamma) (Constitutive coactivator of PPARG); EKLF, Krueppel-like factor 1 (Erythroid krueppel-like transcription factor); ESRRB, Steroid hormone receptor ERR2 (Estrogen receptor-like 2) (Estrogen-related receptor beta) (ERR-beta); PPARD, Peroxisome proliferator-activated receptor delta (PPAR-delta); ZFP42, Zinc finger protein 42; WT1, Wilms tumor protein; NR0B1, Nuclear receptor subfamily 0 group B member 1 (Nuclear receptor DAX-1); TET1, Methylcytosine dioxygenase TET1 (EC 1.14.11.n2) (CXXC-type zinc finger protein 6) (Ten-eleven translocation 1 gene protein homolog); GATA4, Transcription factor GATA-4 (GATA-binding factor 4).

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