Baseline variables used for model development in the training group (p-value <0.15).

nHap_E1E2, number of haplotypes in the whole E1–E2 studied region; nHap_HVR1, number of haplotypes in the hypervariable region 1; ISDR, interferon-sensitivity determining region; SD, standard deviation; Ks, number of substitutions per synonymous site; ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transferase; ×ULN, factor times upper limit of normal used in our center for males and females: 41 and 31 U/L for ALT, 37 and 31 for AST, and 85 and 50 for GGT, respectively.


One missing value in each group.




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