Figure_6.tif (588.79 kB)
Antioxidative effect of landiolol on intact cardiomyocytes.
figure
posted on 2015-01-23, 03:20 authored by Shigeki Kobayashi, Takehisa Susa, Hironori Ishiguchi, Takeki Myoren, Wakako Murakami, Takayoshi Kato, Masakazu Fukuda, Akihiro Hino, Takeshi Suetomi, Makoto Ono, Hitoshi Uchinoumi, Hiroki Tateishi, Mamoru Mochizuki, Tetsuro Oda, Shinichi Okuda, Masahiro Doi, Takeshi Yamamoto, Masafumi YanoRepresentative data. In normal cardiomyocytes, fluorescence intensity of DCFH-DA was significantly increased after addition of 100μmol/L H2O2 and restored to a normal level in the presence of 100μmol/L edaravone, while it remained increased in the presence of 10 nmol/L landiolol.
