Figure_3.tif (553.46 kB)
Analysis of antiviral therapy resistant mutations of Omani HBV isolates.
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posted on 2014-05-16, 03:19 authored by Said Ali Al Baqlani, Bui Tien Sy, Boris A. Ratsch, Khalid Al Naamani, Salah Al Awaidy, Suleiman Al Busaidy, Georg Pauli, C.-Thomas BockThe amino acid sequences of the HBV polymerase (reverse transcriptase region; aa rtM1 to rtL275) of the Omani resistant mutation isolates were aligned with the corresponding region of the reference sequences (HBV-genotypes A to H; GenBank accession numbers are denoted) by ClustalW with Neighbor Joining method and 1000 bootstrap replicates. Described antiviral resistant mutations were highlighted and denoted at the top (e.g., L80V).
